DNA, Genes, & Chromosomes Interactive Simulation | Life Science | Grades 6–8

This Interactive Simulation has grades 6–8 Middle School Life Science students run a hands-on classroom model of DNA, Genes, & Chromosomes.

Driving question: "How does the sequence of nitrogen bases in a DNA gene determine the amino acid sequence, folded structure, and cellular function of a protein?" Objective: Students will build a physical model of a double-stranded DNA gene, decode three-base codons into an amino acid sequence, and test how structural changes to bases affect protein folding and trait expression.

What's inside: objective and background, a materials list (60 color-coded interlocking base beads…; 2 flexible chenille stems (pipe…; 1 set of 20 labeled Amino Acid Folding…; 1 Universal Genetic Codon Decoder Wheel…), an 8-step protocol, a data table, 4 analysis questions, and teacher notes.

Resource type: Interactive Simulation (.docx). Format: editable Microsoft Word lab handout with approximately 920 words (~5 pages).

Classroom use: a team investigation in a Middle School Life Science course. Grades 6–8.

Format note: These files are delivered in Microsoft Office formats (Word and/or PowerPoint). If you open a worksheet that includes tables in Apple Pages or another non-Microsoft app, table formatting may not display correctly. For best results, use Microsoft Word or PowerPoint (or upload the file to Google Docs). If you run into any formatting issues, contact us and we can send a PDF version.