Maryland MISA Biology Comprehensive Study Guide | Biology | Grades 9–12

This Maryland MISA Biology Comprehensive Study Guide is a state assessment prep resource for the Maryland Integrated Science Assessment (MISA) life science exam, written for high school Biology students in grades 9–12 and their teachers.

Pairs with: Maryland MISA Biology Exam Overview and Teacher Guide; Maryland MISA Biology Chapter-to-PE Crosswalk.

Sections: Maryland Ls Misa — State Exam Prep; Structure And Function; Matter And Energy In Organisms And Ecosystems; Interdependent Relationships In Ecosystems; Inheritance And Variation Of Traits; Natural Selection And Evolution; Practice Items. Sample item: “1. A change in one base of a gene changes one amino acid in hemoglobin, and the altered hemoglobin folds differently. Which statement best explains this result?”

What's inside: Study Guide (editable .docx + PDF, about 4,671 words, 19 pages); answer key / model answers for the teacher.

Standards: NGSS High School Life Science performance expectations (HS-LS1 through HS-LS4) as assessed on the Maryland MISA.

Resource type: State Test Prep. Format: editable Microsoft Word file plus a ready-to-print PDF.

Classroom use: Use it to prepare students for the end-of-course state biology assessment. Built for high school Biology, grades 9–12.

Format note: These files are delivered in Microsoft Office formats (Word and/or PowerPoint). If you open a worksheet that includes tables in Apple Pages or another non-Microsoft app, table formatting may not display correctly. For best results, use Microsoft Word or PowerPoint (or upload the file to Google Docs). If you run into any formatting issues, contact us and we can send a PDF version.